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Acting Editor Sophie Gardner sophie.gardner@markallengroup.com Chief Sub Editors Brian Cooper Lindsey Stewart Consultant Editor Tracy Cowan Commercial Manager Emma Blick emma.blick@markallengroup.com Circulation Director Sally Boettcher sally.boettcher@markallengroup.com Production Manager Kyri Apostolou Production Assistant Charlotte Rutland Associate Publisher Sophie Gardner Publishing Director Andrew Iafrati Managing Director Anthony Kerr anthony.kerr@markallengroup.com Chief Executive Officer Ben Allen JWC is available in many libraries and is indexed on several databases, including: • Science Citation Index Expanded and

Current Contents/Clinical Medicine from Thomson Reuters • MEDLINE National Library of Medicine • CINAHL The Cumulative Index to

Nursing and Allied Health Literature • RCN The Royal College of Nursing

Library Nursing Bibliography • HINARI Access to Research in

Health Programme, part of the Research4Life initiative

Cover picture: International Space Station, satellite, orbiting Copyright holder: Adobe Stock/Adam This year’s cover theme is ‘Space’

the monthly international wound-care journal

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JOURNAL OF WOUND CARE VOL 31, NO 4, APRIL 2022 281 281 Editorial: Patient involvement: a necessity not a dream  Editorial: Patient involvement: a necessity not a dream  Zena Moore Zena Moore 282 282 Adipose tissue as a source of growth factors to promote wound healing: a human Adipose tissue as a source of growth factors to promote wound healing: a human study of skin graft donor sites  study of skin graft donor sites  A within-subject study describing the effects of A within-subject study describing the effects of platelet-rich plasma and adipose tissue extract on skin graft donor site wound healing platelet-rich plasma and adipose tissue extract on skin graft donor site wound healing in patients requiring split-thickness skin grafts. Haemoglobin and melanin content, in patients requiring split-thickness skin grafts. Haemoglobin and melanin content, re-epithelialisation area, pain and scar characteristics, and biomaterial samples re-epithelialisation area, pain and scar characteristics, and biomaterial samples were analysed.  were analysed.  Jenny F López, Antti Mikkola, Jertta-Riina Sarkanen, Ilkka S Kaartinen, Jenny F López, Antti Mikkola, Jertta-Riina Sarkanen, Ilkka S Kaartinen, Hannu O Kuokkanen, Timo Ylikomi Hannu O Kuokkanen, Timo Ylikomi 294 294 Sub-epidermal moisture assessment as a prompt for clinical action in treatment of Sub-epidermal moisture assessment as a prompt for clinical action in treatment of pressure ulcers in at-risk hospital patients  pressure ulcers in at-risk hospital patients  The relationship between technology- The relationship between technologygenerated prompts for clinical action and consequent clinical action was evaluated using generated prompts for clinical action and consequent clinical action was evaluated using data cross-tabulations; in a multilevel model with patients clustered within wards, and in data cross-tabulations; in a multilevel model with patients clustered within wards, and in wards within hospitals, and controlling for additional patient- and institution-level factors, wards within hospitals, and controlling for additional patient- and institution-level factors, and using receiver operating characteristic analyses of anatomy-specific data.  and using receiver operating characteristic analyses of anatomy-specific data.  Karen Ousey, Karen Ousey, John Stephenson, Joanna Blackburn John Stephenson, Joanna Blackburn 304 304 Combined use of progressive tension suture and negative pressure wound therapy in Combined use of progressive tension suture and negative pressure wound therapy in large torso degloving wounds  large torso degloving wounds  A case report of two patients with large torso degloving A case report of two patients with large torso degloving wounds caused by trauma, both of whom were treated with combined progressive tension wounds caused by trauma, both of whom were treated with combined progressive tension sutures and negative pressure wound therapy. Statistics related to wound treatment sutures and negative pressure wound therapy. Statistics related to wound treatment responses are presented.  responses are presented.  Fernando AC Spencer Netto, Mariana J Becker, Ayessa Bertoldi, Fernando AC Spencer Netto, Mariana J Becker, Ayessa Bertoldi, Henriqué S Shiroma, Hemanuelli Barreto, Marcelo Augusto Fontenelle Ribeiro Jr Henriqué S Shiroma, Hemanuelli Barreto, Marcelo Augusto Fontenelle Ribeiro Jr 310 310 Use of injectable acellular dermal matrix combined with negative pressure wound Use of injectable acellular dermal matrix combined with negative pressure wound therapy in open diabetic foot amputation  therapy in open diabetic foot amputation  A retrospective study of 41 patients, treated A retrospective study of 41 patients, treated either with negative pressure wound therapy (NPWT) only or with injectable acellular either with negative pressure wound therapy (NPWT) only or with injectable acellular dermal matrix combined with NPWT. Number of NPWT dressing changes, wound dermal matrix combined with NPWT. Number of NPWT dressing changes, wound healing duration, and full-thickness skin graft incident rate between the two groups were healing duration, and full-thickness skin graft incident rate between the two groups were compared. compared.  Jiyong Ahn, Ho Youn Park, Asode Ananthram Shetty, Wonha Hwang Jiyong Ahn, Ho Youn Park, Asode Ananthram Shetty, Wonha Hwang 322 322 Effect of a wound healing protocol on patients with stage III and IV pressure ulcers: a Effect of a wound healing protocol on patients with stage III and IV pressure ulcers: a preliminary observational study  preliminary observational study  Patients were recruited from 10 acute care settings of an Patients were recruited from 10 acute care settings of an Italian university hospital, and managed with a protocol inspired by the TIMECare model. Italian university hospital, and managed with a protocol inspired by the TIMECare model. Wound healing was assessed with the Pressure Ulcer Scale for Healing. Nutritional status Wound healing was assessed with the Pressure Ulcer Scale for Healing. Nutritional status was assessed with the Mini Nutritional Assessment Index.  was assessed with the Mini Nutritional Assessment Index.  Dario Monaco, Francesco Zaghini, Dario Monaco, Francesco Zaghini, Jacopo Fiorini, Giulia Venturini, Paolo Iovino, Ercole Vellone, Rosaria Alvaro, Alessandro Sili Jacopo Fiorini, Giulia Venturini, Paolo Iovino, Ercole Vellone, Rosaria Alvaro, Alessandro Sili 330 330 Hydro-responsive wound dressings for treating hard-to-heal wounds: a narrative review Hydro-responsive wound dressings for treating hard-to-heal wounds: a narrative review of the clinical evidence—part 2  of the clinical evidence—part 2  This review demonstrates how HRWD-2 can be used This review demonstrates how HRWD-2 can be used in general to address the challenges presented by a wide range of wound types and skin in general to address the challenges presented by a wide range of wound types and skin injuries, and its ability to regulate an optimal moist wound environment that promotes injuries, and its ability to regulate an optimal moist wound environment that promotes wound progression and healing.  wound progression and healing.  Mark G Rippon, Jan Forster, Alan A Rogers Mark G Rippon, Jan Forster, Alan A Rogers 340 340 IV3000 semi-occlusive dressing use in simple and complex fingertip injuries: efficacy and IV3000 semi-occlusive dressing use in simple and complex fingertip injuries: efficacy and affordability affordability  In this qualitative study, 64 patients with any fingertip injury with tissue loss In this qualitative study, 64 patients with any fingertip injury with tissue loss were prospectively recruited and treated conservatively with the IV3000 semi-occlusive, were prospectively recruited and treated conservatively with the IV3000 semi-occlusive, transparent adhesive film dressing.  transparent adhesive film dressing.  Catherine Jenn Yi Cheang, Muhammad Adil Abbas Khan, Catherine Jenn Yi Cheang, Muhammad Adil Abbas Khan, Daniel J Jordan, Kazem Nassar, Dujanah Siddique Bhatti, Sadia Rafiq, Fiona J Hogg, Daniel J Jordan, Kazem Nassar, Dujanah Siddique Bhatti, Sadia Rafiq, Fiona J Hogg, Stuart W Waterston Stuart W Waterston 348 348 The effects of negative pressure wound therapy on wounds with cerebrospinal fluid The effects of negative pressure wound therapy on wounds with cerebrospinal fluid leakages leakages  A longitudinal prospective study of 12 patients. Outcome measures evaluated A longitudinal prospective study of 12 patients. Outcome measures evaluated were changes in the level of consciousness, Glasgow Coma Scale score, length of hospital were changes in the level of consciousness, Glasgow Coma Scale score, length of hospital stay, mean effluent collected, time taken for the wounds to heal/close and complications stay, mean effluent collected, time taken for the wounds to heal/close and complications related to negative pressure wound therapy.  related to negative pressure wound therapy.  Ferdinand Wanjala Nangole, George Agak Ferdinand Wanjala Nangole, George Agak 352 352 Bacterial protease activity: a prognostic biomarker of early wound infection  Bacterial protease activity: a prognostic biomarker of early wound infection  Participants Participants were drawn from six US wound centres and had their wounds assessed clinically for were drawn from six US wound centres and had their wounds assessed clinically for infection. Wound fluid swabs were collected and analysed for bacterial protease activity, infection. Wound fluid swabs were collected and analysed for bacterial protease activity, inflammatory cytokines (interleukin-1 inflammatory cytokines (interleukin-1β, interleukin-6 and tumour necrosis factor- , interleukin-6 and tumour necrosis factor-α), and ), and cultured for quantitative microbiology  cultured for quantitative microbiology  Thomas E Serena, Simon W Bayliff, Patrick J Brosnan Thomas E Serena, Simon W Bayliff, Patrick J Brosnan 356 356 Pain control with punch grafting in ulcers with underlying arteriolosclerosis  Pain control with punch grafting in ulcers with underlying arteriolosclerosis  A single- A singlecentre retrospective study of 40 patients with a clinical diagnosis of a Martorell ulcer or centre retrospective study of 40 patients with a clinical diagnosis of a Martorell ulcer or post-traumatic ulcer secondary to arteriolopathy. Effectiveness of punch grafting compared post-traumatic ulcer secondary to arteriolopathy. Effectiveness of punch grafting compared with conventional therapy in pain reduction was assessed.  with conventional therapy in pain reduction was assessed.  Lucía Quintana-Castanedo, Lucía Quintana-Castanedo, Elena Conde-Montero, Lorena Recarte-Marín, Alicia Peral-Vázquez, Laura Pérez-Jerónimo, Elena Conde-Montero, Lorena Recarte-Marín, Alicia Peral-Vázquez, Laura Pérez-Jerónimo, Pablo de la Cueva-Dobao Pablo de la Cueva-Dobao

S1–S45 S1–S45 Silk Road Supplement  Silk Road Supplement  This edition of the supplement features a novel method of This edition of the supplement features a novel method of skin graft fixation using adhesive hydrofiber foam, the use of single-layer artificial skin graft fixation using adhesive hydrofiber foam, the use of single-layer artificial dermal template in trauma and burn patients, a systematic review and meta-analysis dermal template in trauma and burn patients, a systematic review and meta-analysis of wound healing in second-degree burns in rats treated with silver sulfadiazine, risk of wound healing in second-degree burns in rats treated with silver sulfadiazine, risk categorisation of patients attending a diabetic foot screening clinic in Suez, and the categorisation of patients attending a diabetic foot screening clinic in Suez, and the modified application of vacuum-assisted closure in thoracic surgery patients. modified application of vacuum-assisted closure in thoracic surgery patients.

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