Index female sex (prejudice) 157 nucleic acids 47-51 Franklin, Rosalind 56

abortion 151-3

fruit flies, study of 32-9, operons 70

albinism 26

amino acids 48, 64-5

104

mutations 44-6

Pauling, Linus 56

animals, genetic engineering 143

antigens 149

atavism 25

Auerbach , Charlotte 45 genes

PCR 83

Gaitan, Francis 11-13, 156 peas 15-21

Gallon Laboratory 27 pedigrees 24, 26

Garrod , Archibald 31 phages 52, 61

plasmids 81

defined 5

pneumonia 49

bacterial mating 67-71,

79-82

blood cells, red 87-9

brain genes 124

dominant/recessive 19 politics 41 , 17 4-5

linkage map 40-1, 78 polymerases 60, 83

replacing faulty 144-5 prions 1 08-9

transferring 166 genetic proteins 47-8 , 77

cancer 146-7 , 162-3

cells 74-5 , 87-9

diseases, curing 11 recessive genes 19, 25,

engineering 139-65

26, 33

chromosomes 34-44, 100 map 122, 125-7 , 136 restriction enzymes 80

bacterial genes 67-71 genetically modified foods retroviruses 110-11 defined 77 174 RNA51,63 see also DNA; YACs germ-line therapy 150-1 , see also mRNA, tRNA Churchill, Winston 28 154 cloning 81, 17 4-5 Sager, Ruth 73 codes 77 haemoglobin 87-8 screening 133-6 , 158-9 conception 75 heredity 76 sex cells 75, 76 Crick , Francis 54-63 Hitler, Adolf 28 Shaw, G.B. 28 criminal tendency 156 HIV virus 111 sickle-cell anaemia 158 cystic fibrosis 117-21, 153 human Stalin, Joseph 42

screening for 132-5

treating 137-9 , 144

egg 75

starvation , easing 17 4

inheritance 23

stem cells 17 4-5

Huntington's Disease 160 Stopes , Marie 27

Darwin, Charles 8-9

disease, predicting see inheritance, human 23

Sturtevant, A.H. 39-40

screening insurance, health 165, 173 Tay-Sachs Disease 115,

disease, inherited 114-23 , intelligence 155

131

128-53 , 158, 173-4

DNA 51ft artificial 64

codes 53-65, 77

transcription 63

Jenkin , Fleeming 9-10 translation 63

kidney failure 161

transforming principle 50

tRNA 77

in conception 75 creating 79-85

Laboratory for National variation in genetics 29

heredity 76-7

length 73

mapping 78-113

Eugenics 13, 27

linkage map 40-1 , 78

Lysenko, T. D. 42-3

migratory 101-5

dominant genes 19, 33 mapping double helix 56-9

DNA 78-113 genes 122

viruses 52, 80-1 , 1 06-9

genetic engineering 142

see also HIV virus ;

retroviruses

Vries, Hugo de 30

Watson, James 54-63

egg, human 75

electrophoresis 84

enzymes 31, 77

McClintock, Barbara 101 wobble theory 65

Mendel, Gregor 14-23

mice 148

X-rays 45-6

see also polymerases ; Miescher, J.F. 46-7

and DNA 56

restriction enzymes Morgan, Thomas Hunt 32-8 Eugenics Society 27 mRNA63, 77 YACs (yeast artificial eye colour 33-8 mutations 30, 44-6, 60, chromosomes) 82

66, 101-5